Open AccessAnalysis of Risk Factors Associated with Reduced Trough Concentrations of Vancomycin in Relation to Renal Function in a Tertiary Hospital in Japan
Author(s) -
Shota Kashiwagura,
Yasuhiro Kamioka,
Masafumi Seki,
Satoshi Koshika,
Kouji Okada
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s337058
Subject(s) - renal function , trough concentration , medicine , trough level , vancomycin , multivariate analysis , urology , gastroenterology , surgery , biology , pharmacokinetics , staphylococcus aureus , bacteria , transplantation , genetics , tacrolimus
Low trough concentrations of vancomycin (VCM) are common in patients receiving the drug, because patients are often administered relatively low doses of VCM due to its high potential for renal toxicity. However, the clinical risk factors associated with low VCM trough concentration in relation to renal function are unclear.