Open AccessHighly Suspected COVID-19 Cluster with Multiple Negative SARS-CoV-2 RNA Tests: A Case Report
Author(s) -
Xialing Huang,
Xiaoping Long,
Jun Zi,
Ping Liu
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s336873
Subject(s) - covid-19 , negativity effect , medicine , cluster (spacecraft) , virology , rna , biology , outbreak , psychology , genetics , gene , infectious disease (medical specialty) , social psychology , disease , computer science , programming language
The patient had several close contacts with friends from Wuhan, the epicenter of the epidemic. His mother and father had close contact with him. His father was later diagnosed with COVID-19 infection after a positive reverse transcription PCR test for SARS-CoV-2 RNA. The patient and his mother were diagnosed as suspected cases of COVID-19 based on a history of exposure, clinical manifestation, and imaging examination. However, the patient was tested more than three times with the reverse transcription PCR test for SARS-CoV-2 RNA, and the results were negative each time. COVID-19 should be suspected, regardless of SARS-CoV-2 test negativity, for recent close contact with a confirmed case and respiratory symptoms.