Open AccessMagnitude of Antibody Cross-Reactivity in Medically Important Mosquito-Borne Flaviviruses: A Systematic Review
Author(s) -
Adugna Endale,
Girmay Medhin,
Koyamo Darfiro,
Nigatu Kebede,
Mengistu Legesse
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s336351
Subject(s) - virology , serology , dengue fever , chikungunya , flavivirus , zika virus , dengue virus , cross reactivity , antibody , japanese encephalitis , alphavirus , biology , virus , immunoglobulin m , encephalitis , medicine , immunology , immunoglobulin g , cross reactions
Flaviviruses are a genus of enveloped single-stranded RNA viruses that include dengue virus (DENV), yellow fever virus, West Nile virus (WNV), Japanese encephalitis virus, and Zika virus. Nowadays, diverse serological assays are available to diagnose flaviviruses. However, infection with flaviviruses induces cross-reactive antibodies, which are a challenge for serological diagnosis.