Open AccessAppropriateness of Empirical Fluoroquinolones Therapy in Patients Infected with Escherichia coli, Klebsiella pneumoniae, or Pseudomonas aeruginosa: The Importance of the CLSI Breakpoints Revision
Author(s) -
Ying Wang,
Xinping Zhang,
Xuemei Wang,
Xiaoquan Lai
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s329477
Subject(s) - ciprofloxacin , klebsiella pneumoniae , levofloxacin , pseudomonas aeruginosa , antimicrobial , antibiotics , medicine , microbiology and biotechnology , klebsiella , antibiotic resistance , escherichia coli , bacteria , biology , biochemistry , genetics , gene
Empirical antibiotic therapy should follow the local bacterial susceptibility, and the breakpoints revisions of the antimicrobial susceptibility testing can reflect the changes in the antimicrobial susceptibility of bacteria. This study aimed to analyze whether the changes in the antimicrobial susceptibility to antibiotics caused by the breakpoint revision will affect the empirical antibiotic therapy and its appropriateness.