Open AccessClinical Comparison of Three Sample-to-Answer Systems for Detecting SARS-CoV-2 in B.1.1.7 Lineage Emergence
Author(s) -
Ming-Jr Jian,
Hsing-Yi Chung,
ChiungWen Chang,
JungChung Lin,
Kuo-Ming Yeh,
Chien-Wen Chen,
Shih-Yi Li,
Shan-Shan Hsieh,
MingTsan Liu,
Ji-Rong Yang,
Shenghui Tang,
CherngLih Perng,
Feng–Yee Chang,
HungSheng Shang
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s328327
Subject(s) - covid-19 , point of care testing , medicine , virology , lineage (genetic) , molecular diagnostics , gold standard (test) , immunology , biology , bioinformatics , gene , genetics , infectious disease (medical specialty) , disease
Accurate molecular diagnostic assays for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, are needed for epidemiology studies and to support infection-control measures. We evaluated the analytical sensitivity and clinical performance of three sample-to-answer molecular-diagnostics systems for detecting SARS-CoV-2 using 325 nasopharyngeal swab clinical samples from symptomatic patients.