Open AccessThe Transcription Factor Rv1453 Regulates the Expression of qor and Confers Resistant to Clofazimine in Mycobacterium tuberculosis
Author(s) -
Yuanyuan Li,
Ling Fu,
Weiyan Zhang,
Xi Chen,
Yu Lu
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s324043
Subject(s) - clofazimine , mycobacterium tuberculosis , electrophoretic mobility shift assay , transcription (linguistics) , biology , microbiology and biotechnology , reverse transcriptase , transcription factor , chemistry , gene , tuberculosis , biochemistry , polymerase chain reaction , immunology , medicine , leprosy , linguistics , philosophy , pathology
Clofazimine plays an important role in the treatment of drug-resistant tuberculosis. However, the mechanism of clofazimine resistance remains unclear. In order to slow down the occurrence of clofazimine resistance, it is necessary to study its resistance mechanism.