Open AccessDirect-on-Target Microdroplet Growth Assay Applications for Clinical Antimicrobial Susceptibility Testing
Author(s) -
Rongrong Li,
Hao Tang,
Huaming Xu,
Yingli Ren,
Shujin Li,
Jilu Shen
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s303187
Subject(s) - antimicrobial , computational biology , microbiology and biotechnology , biology
Direct-on-target microdroplet growth assay is a new technique for analysing bacterial sensitivity and mechanisms of resistance. It is based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and allows for easy and rapid testing. Here, we describe the development and procedure of the direct-on-target microdroplet growth assay and summarise the latest clinical applications.