Open Access<p>Optimal Empiric Treatment for <em>Klebsiella pneumoniae</em> Infections in Short-Stay ICU Patients During Continuous Renal Replacement Therapy: Results from a Population Pharmacokinetic/Pharmacodynamic Analysis</p>
Author(s) -
Yuqi Jin,
Haiyan Mao,
Liu Bingyang,
Fuxiang Zhou,
Junjie Yang,
Lei Xu,
Jingtao Tong,
Can Huang,
Yi Ding
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s284754
Subject(s) - medicine , pharmacodynamics , klebsiella pneumoniae , renal replacement therapy , pharmacokinetics , population pharmacokinetics , population , pharmacology , biology , escherichia coli , gene , biochemistry , environmental health
There is a paucity of published data to evaluate the efficacy and safety of imipenem (IPM) and piperacillin-tazobactam (PT) dosing regimens in the treatment of septic patients acquiring continuous renal replacement therapy (CRRT).