Open Access<p>Antibiogram and Genetic Characterization of Carbapenem-Resistant Gram-Negative Pathogens Incriminated in Healthcare-Associated Infections</p>
Author(s) -
Rabab R. Makharita,
Iman El-Kholy,
Helal F. Hetta,
Moahmed H Abdelaziz,
Fatma I Hagagy,
Amera Ali Ahmed,
Abdelazeem M. Algammal
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s276975
Subject(s) - microbiology and biotechnology , acinetobacter baumannii , carbapenem , klebsiella pneumoniae , colistin , pseudomonas aeruginosa , proteus mirabilis , enterobacter aerogenes , biology , acinetobacter , antibiotic resistance , antibiotics , escherichia coli , bacteria , gene , biochemistry , genetics
Carbapenems are considered the most efficient antibiotic used in the treatment of nosocomial infections. Carbapenem-resistant Gram-negative rods are becoming a serious hazard in hospitals threatening public health. The aim of the current study was to investigate the prevalence of carbapenem-resistant Gram-negative pathogens incriminated in healthcare-associated infections, along with antimicrobial resistance profiles, carbapenemase and metallo-β-lactamase production, and their molecular characterization.