Open AccessPseudomonas aeruginosa Type III Secretion System Virulotypes and Their Association with Clinical Features of Cystic Fibrosis Patients
Author(s) -
Edilene do Socorro Nascimento Falcão Sarges,
Yan Corrêa Rodrigues,
Ismari Perini Furlaneto,
Marcos Vinícios Hino de Melo,
Giulia Leão da Cunha Brabo,
Kátia Cilene Machado Lopes,
Ana Judith Pires Garcia Quaresma,
Luaepomuceno Godim Costa Lima,
Karla Valéria Batista Lima
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s273759
Subject(s) - pseudomonas aeruginosa , cystic fibrosis , medicine , secretion , microbiology and biotechnology , biology , bacteria , genetics
Pseudomonas aeruginosa appears as the main pathogen in cystic fibrosis (CF) involved in recurrent pneumonia and pulmonary exacerbations. The type III secretion system (T3SS) is one of its main determinants of virulence and is associated with poor clinical progression and increased mortality. This study determined the relationship of clinical features of patients with CF and P. aeruginosa T3SS virulotypes.