Open Access<p>UPLC-MS/MS Measurement of the Effect of Isavuconazole, Itraconazole and Fluconazole on the Pharmacokinetics of Selinexor in Rats</p>
Author(s) -
Shuang-long Li,
Yi Zhang,
Qian-shi Cheng,
Jun-zhe Xin,
Ze-qin Dong,
Xiangjun Qiu
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s269831
Subject(s) - itraconazole , fluconazole , pharmacokinetics , pharmacology , antifungal , chemistry , medicine , dermatology
An ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the determination of selinexor was established to investigate the effects of isavuconazole, itraconazole and fluconazole on the pharmacokinetics of selinexor in rats, respectively.