Open Access<p>Optimized Production of the Allylamine Antifungal “Terbinafine” by <em>Lysinibacillus</em> Isolate MK212927 Using Response Surface Methodology</p>
Author(s) -
Sayed E. El-Sayed,
Ghadir S. El-Housseiny,
Neveen A. Abdelaziz,
Mona R El-Ansary,
Khaled M. Aboshanab
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s267590
Subject(s) - terbinafine , allylamine , antifungal , metabolite , chemistry , ammonium chloride , response surface methodology , nuclear chemistry , chromatography , food science , microbiology and biotechnology , biology , biochemistry , organic chemistry , itraconazole , polyelectrolyte , polymer
We aimed to optimize the factors affecting the production of the allylamine antifungal, terbinafine, by Lysinibacillus isolate MK212927, a natural producer of this broad-spectrum fungicidal compound.