Open Access<p><em>Cucurbita pepo</em> Seed Oil Induces Microsatellite Instability and Tegumental Damage to <em>Schistosoma mansoni</em> Immature and Adult Worms In vitro</p>
Author(s) -
Amany I. Ammar,
Amira F. Afifi,
Abdallah Essa,
Asmaa Galal-Khallaf,
Mostafa Mokhtar,
Somaia Shehab-Eldeen,
Amany A. Rady
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s265699
Subject(s) - schistosoma mansoni , biology , praziquantel , cucurbita pepo , cucurbita , schistosomiasis , pumpkin seed , microsatellite , immunology , helminths , botany , genetics , food science , gene , allele
Schistosomiasis is a tropical parasitic disease treated exclusively with praziquantel (PZQ). However, PZQ has low efficacy against schistosomula and juveniles. In addition, the emergence of PZQ resistance has prompted the search for new drugs.