Open Access<p>Oral Prevalence of <em>Candida</em> Species in Patients Undergoing Systemic Glucocorticoid Therapy and the Antifungal Sensitivity of the Isolates</p>
Author(s) -
Jialing Xiao,
Guochao Xu,
Sybren de Hoog,
Jianjun Qiao,
Hong Fang,
Yali Li
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s262311
Subject(s) - caspofungin , fluconazole , micafungin , itraconazole , medicine , anidulafungin , voriconazole , amphotericin b , internal transcribed spacer , oral microbiology , gastroenterology , antifungal , biology , dermatology , biochemistry , genetics , bacteria , ribosomal rna , gene
Candida species are commonly detected as colonizers of the oral cavity; candidiasis or candidemia can develop in patients who are immunocompromised. Use of topical or inhaled glucocorticoids can alter the spectrum of Candida species and can promote oral candidiasis. The present study aims to evaluate the diversity of Candida species in the oral cavity and their susceptibility to antifungal agents in patients undergoing treatment with systemic glucocorticoids (SGCs) compared with non-users.