Open Access<p>NDM-1 Carbapenemase-Producing Enterobacteriaceae are Highly Susceptible to Ceragenins CSA-13, CSA-44, and CSA-131</p>
Author(s) -
Sylwia Chmielewska,
Karol Skłodowski,
Ewelina Piktel,
Łukasz Suprewicz,
Krzysztof Fiedoruk,
Tamara Daniluk,
Przemysław Wolak,
Paul B. Savage,
Robert Bucki
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s261579
Subject(s) - klebsiella pneumoniae , biofilm , enterobacter cloacae , microbiology and biotechnology , enterobacteriaceae , escherichia coli , chemistry , bacteria , citrobacter freundii , bacterial outer membrane , biology , biochemistry , genetics , gene
Treatment of infections caused by NDM-1 carbapenemase-producing Enterobacteriaceae (CPE) represents one of the major challenges of modern medicine. In order to address this issue, we tested ceragenins (CSAs - cationic steroid antimicrobials) as promising agents to eradicate various NDM-1-producing Gram-negative enteric rods.