Open Access<p>A 9-Year Experience of <em>Aspergillus</em> Infections from Isfahan, Iran</p>
Author(s) -
Mostafa Chadeganipour,
Rasoul Mohammadi
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s259162
Subject(s) - aspergillus terreus , aspergillus , aspergillus flavus , aspergillus niger , aspergillosis , microbiology and biotechnology , amphotericin b , voriconazole , medicine , veterinary medicine , biology , aspergillus fumigatus , agar , immunology , antifungal , bacteria , genetics
Aspergillosis is an important fungal disease affecting millions of individuals worldwide. The genus of Aspergillus consist of various complexes, causing a wide spectrum of diseases from superficial infections in immunocompetent hosts to life-threatening disseminated infections among immunocompromised patients. This study aimed to identify Aspergillus species by phenotypic (total isolates) and molecular tests (35 isolates), obtained from patients in Isfahan (the third-largest city of Iran) between 2010 and 2018, and determine the susceptibility of 35 clinical isolates to itraconazole (ITR), amphotericin-B (AMB), and voriconazole (VOR).