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Combined HIV infection can accelerate HBV-induced liver disease. It is known that HBV Pre-S deletion is closely related to HBV-associated terminal liver disease in HBV mono-infection. Currently, data on HBV Pre-S quasispecies feature deletion in HIV/HBV co-infected patients are lacking.

<p>Pre-S Deletions are Predominant Quasispecies in HIV/HBV Infection: Quasispecies Perspective</p>