Open Access<p>High Prevalence of 16S rRNA Methyltransferase Genes in Carbapenem-Resistant <em>Klebsiella pneumoniae</em> Clinical Isolates Associated with Bloodstream Infections in 11 Chinese Teaching Hospitals</p>
Author(s) -
Xiaofei Shen,
Li Liu,
Jingyi Yu,
Wenxiu Ai,
Xingwei Cao,
Qing Zhan,
Yinjuan Guo,
Liangxing Wang,
Fangyou Yu
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s254479
Subject(s) - multilocus sequence typing , 16s ribosomal rna , klebsiella pneumoniae , biology , microbiology and biotechnology , amikacin , pulsed field gel electrophoresis , gene , genotype , genetics , antibiotics , escherichia coli
The 16S rRNA methylase-mediated high-level resistance to aminoglycosides has become a great concern. The purpose of the study was to investigate the occurrence of 16S rRNA methyltransferase (RMTase) genes in carbapenem-resistant Klebsiella pneumoniae (CRKP) clinical isolates associated with bloodstream infections (BSIs) in China.