Open Access<p>Comparison of Microdilution Method with Agar Dilution Method for Antibiotic Susceptibility Test of <em>Neisseria gonorrhoeae</em></p>
Author(s) -
Shao-Chun Chen,
Jing-Wei Liu,
Xingzhong Wu,
Wenling Cao,
Feng Wang,
Jinmei Huang,
Yang Han,
Xiaoyu Zhu,
Bang-Yong Zhu,
Quan Gan,
Xiaozheng Tang,
Xing Shen,
Xiaolin Qin,
Yuqi Yu,
Heping Zheng,
Yue-Ping Yin
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s253811
Subject(s) - neisseria gonorrhoeae , spectinomycin , ciprofloxacin , ceftriaxone , penicillin , azithromycin , broth microdilution , antibiotic resistance , agar dilution , medicine , microbiology and biotechnology , antimicrobial , tetracycline , antibiotics , biology , minimum inhibitory concentration
Antimicrobial resistance (AMR) of Neisseria gonorrhoeae ( N. gonorrhoeae ) becomes a grave public health problem in the world. A strengthened Antimicrobial Resistance Surveillance Program is needed to track the trend of AMR development. However, the lack of a proper antimicrobial susceptibility test (AST) method is a barrier to expand the AMR surveillance in China. Traditional agar dilution (AD) method is laborious and E-test strips have no approval license for clinical use. Herein, a Chinese group modified the microdilution (MD) method for clinical ASTs. The objective of this study is to compare the MD method with the AD method for N. gonorrhoeae AST.