Open Access<p>Prevalence of Potential Resistance Related Variants Among Chinese Chronic Hepatitis B Patients Not Receiving Nucleos(T)ide Analogues</p>
Author(s) -
Fuchu Qian,
Weihua Zou,
Jiayi Fang,
Dongli Li,
Yujuan Shen
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s249476
Subject(s) - genotype , hepatitis b virus , medicine , hepatitis b , drug resistance , chronic hepatitis , logistic regression , gastroenterology , reverse transcriptase , polymerase chain reaction , virology , biology , virus , gene , genetics
Potential drug resistance (DR) related variants in the hepatitis B virus (HBV) reverse transcriptase (RT) region may be associated with the effectiveness of antiviral drugs and disease progression. The aim of this study was to investigate the prevalence and clinical characteristics of potential DR-related variants in Chinese CHB patients not receiving nucleos(t)ide analogues (NAs).