Open Access<p>Discovery of Potential Plasma Biomarkers for Tuberculosis in HIV-Infected Patients by Data-Independent Acquisition-Based Quantitative Proteomics</p>
Author(s) -
Yinzhong Shen,
Jingna Xun,
Wei Song,
Zhenyan Wang,
Jiangrong Wang,
Li Liu,
Renfang Zhang,
Tangkai Qi,
Yang Tang,
Jun Chen,
Jianjun Sun,
Hongzhou Lu
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s245460
Subject(s) - tuberculosis , mycobacterium tuberculosis , proteomics , human immunodeficiency virus (hiv) , lactate dehydrogenase , medicine , quantitative proteomics , tandem mass tag , immunology , biology , enzyme , pathology , biochemistry , gene
Tuberculosis (TB) is the leading cause of mortality in individuals infected with human immunodeficiency virus (HIV), yet the methods for detecting Mycobacterium tuberculosis at an early stage remain insensitive or ineffective. This study aimed to discover plasma biomarkers for distinguishing HIV-TB coinfected individuals from HIV individuals without TB (HIV-nonTB).