Open Access<p>Nanoparticles-Based Biosensor Coupled with Multiplex Loop-Mediated Isothermal Amplification for Detection of <em>Staphylococcus aureus</em> and Identification of Methicillin-Resistant <em>S. aureus</em></p>
Author(s) -
Jiang Lei,
Yongming Li,
Rumeng Gu,
Deguang Mu
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s243881
Subject(s) - staphylococcus aureus , loop mediated isothermal amplification , multiplex , microbiology and biotechnology , methicillin resistant staphylococcus aureus , biosensor , chemistry , biology , bacteria , dna , bioinformatics , biochemistry , genetics
Staphylococcus aureus ( S. aureus ), including methicillin-resistant S. aureus (MRSA), is a common human pathogen, which can cause a variety of infections from mild to severe. In this article, a new diagnostic method called multiplex loop-mediated isothermal amplification combined with nanoparticles-based lateral flow biosensor (mLAMP-LFB) has been developed, which was proved to be fast, reliable, and simple for detecting S. aureus , and differentiate MRSA from methicillin-susceptible S. aureus (MSSA).