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Dendritic cells (DCs) with both proinflammatory and tolerogenic properties have been implicated in modulation of CD4 + T cell responses in many fungal diseases. However, the role of DC in the context of Talaromyces marneffei ( T. marneffei ) infection has not been determined. In this study, we aimed to study the effect of the yeast form of T. marneffei yeasts on DCs, as well as the role of DCs in modulating T helper 17 (Th17) and regulatory T (Treg) cell responses to the pathogen.

infection and drug resistance

&lt;p&gt;Dendritic Cells Promote Treg Expansion but Not Th17 Generation in Response to &lt;em&gt;Talaromyces marneffei&lt;/em&gt; Yeast Cells&lt;/p&gt;