Open Access<p>Mutations in the Antibiotic Target Genes Related to Clarithromycin, Metronidazole and Levofloxacin Resistance in <em>Helicobacter pylori</em> Strains from Children in China</p>
Author(s) -
Yanyi Zhang,
Yi Wen,
Qiulin Xiao,
Wei Zheng,
Long Gao,
Bo Chen,
Xiaoli Shu,
Mizu Jiang
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s235615
Subject(s) - levofloxacin , 23s ribosomal rna , clarithromycin , metronidazole , helicobacter pylori , microbiology and biotechnology , antibiotics , biology , mutation , antibiotic resistance , gene , genetics , ribosome , rna
This study aimed to characterize common mutations of antibiotic-resistant gene of clarithromycin, metronidazole and levofloxacin in Helicobacter pylori ( H. pylori ) and determine their association with antibiotic resistance of H. pylori for providing a strategy for eradication therapy of H. pylori infection in children.