Open Access<p>Molecular Epidemiology and Mechanisms of High-Level Resistance to Meropenem and Imipenem in <em>Pseudomonas aeruginosa</em></p>
Author(s) -
Noha A. Hassuna,
Marwa K. Darwish,
Mohamed Sayed,
Reham Ali Ibrahem
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s233808
Subject(s) - pseudomonas aeruginosa , efflux , meropenem , imipenem , microbiology and biotechnology , biology , antibiotic resistance , antimicrobial , carbapenem , drug resistance , antibiotics , bacteria , genetics
Pseudomonas aeruginosa possesses a large number of resistance mechanisms to different antimicrobials with carbapenems being the most powerful in treating resistant P. aeruginosa . Hence, it is imperative to explore different mechanisms of carbapenems-resistance in P . aeruginosa to achieve successful treatment through the design of new drugs acting on this interaction to combat against antimicrobial resistance.