Open Access<p>Characterization of the IncFII-IncFIB(pB171) Plasmid Carrying <em>bla</em><sub>NDM-5</sub> in <em>Escherichia coli</em> ST405 Clinical Isolate in Japan</p>
Author(s) -
Yoko Takayama,
Tsuyoshi Sekizuka,
Hidehito Matsui,
Yuzuru Adachi,
Ryotaro Eda,
Shin Nihonyanagi,
Takahiro Wada,
Mari Matsui,
Satowa Suzuki,
Masashi Takaso,
Hidero Kitasato,
Makoto Kuroda,
Hideaki Hanaki
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s232943
Subject(s) - plasmid , multilocus sequence typing , replicon , escherichia coli , biology , whole genome sequencing , microbiology and biotechnology , cephalosporin , genome , enterobacteriaceae , genetics , gene , antibiotics , genotype
New Delhi metallo-β-lactamase 5 (NDM-5) shows stronger resistance to carbapenems and broad-spectrum cephalosporins than NDM-1 because NDM-5 differs from NDM-1 by two amino acid substitutions. In this study, our aim was to characterize a NDM-5-producing Escherichia coli isolate KY1497 from a patient with urinary tract infection in Japan, who had no recent history of overseas travel.