Open Access<p>Structural Genomics of <em>repA, repB1</em>-Carrying IncFIB Family pA1705-<em>qnrS</em>, P911021-<em>tetA</em>, and P1642-<em>tetA</em>, Multidrug-Resistant Plasmids from<em> Klebsiella pneumoniae</em></p>
Author(s) -
Amizir,
Yachao Zhao,
Manli Li,
Rakia Manzoor,
Rana Adnan Tahir,
Xianglilan Zhang,
Hong Qing,
Yigang Tong
Publication year - 2020
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s228704
Subject(s) - plasmid , biology , genetics , klebsiella pneumoniae , insertion sequence , gene , transposable element , inverted repeat , origin of replication , genome , escherichia coli
Multidrug-resistant plasmids carrying replication genes have been widely present in various strains of Klebsiella pneumoniae. RepA and repB1 were found in plasmids belong to the IncFIB, but their detailed structural and genomic characterization was not reported yet. This is the first study that delivers structural and functional insights of repA- and repB1 -carrying IncFIB plasmids.