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The spread of the plasmid-mediated, colistin-resistance gene mcr-1 into New Delhi metallo-β-lactamase (NDM)-producing bacterial isolates can cause untreatable infections. In this study, we conducted a molecular characterization of a novel, conjugative, bla  NDM-5 -positive IncFII plasmid (pNDM-EC16-50) together with an mcr-1 -bearing IncI2 plasmid in a single Escherichia coli ST167 clinical isolate EC16-50.

infection and drug resistance

&lt;p&gt;Characterization of a novel &lt;em&gt;bla&lt;/em&gt;&lt;sub&gt;NDM-5&lt;/sub&gt;-harboring IncFII plasmid and an &lt;em&gt;mcr-1&lt;/em&gt;-bearing IncI2 plasmid in a single &lt;em&gt;Escherichia coli&lt;/em&gt; ST167 clinical isolate&lt;/p&gt;