Open Access<p>Effect of Oral Administration of <em>Weissella confusa</em> on Fecal and Plasma Ethanol Concentrations, Lipids and Glucose Metabolism in Wistar Rats Fed High Fructose and Fat Diet</p>
Author(s) -
Fouad M. F. Elshaghabee,
Darab Ghadimi,
Diana Habermann,
Michael de Vrese,
Wilhelm Bockelmann,
Hans-Jürgen Kaatsch,
Knut J. Heller,
Jürgen Schrezenmeir
Publication year - 2020
Publication title -
hepatic medicine
Language(s) - English
Resource type - Journals
ISSN - 1179-1535
DOI - 10.2147/hmer.s254195
Subject(s) - fructose , feces , oral administration , food science , chemistry , medicine , biology , endocrinology , microbiology and biotechnology
In previous investigations, Weissella confusa was shown to lack the metabolic pathway from fructose to mannitol and to produce ethanol when cultivated in the presence of fructose. Hence, we assessed the effect of oral administration of W. confusa (strain NRRL-B-14171) on blood and fecal ethanol concentrations, glucose and lipid metabolism and traits of the metabolic syndrome in Wistar rats (n=27) fed diets with two different fat and fructose levels and with or without the addition of W. confusa during a total intervention time of 15 weeks (105 days).