Open AccessPerformance of Xpert MTB/RIF Ultra for the Diagnosis of Pulmonary Tuberculosis Using Bronchoalveolar Lavage Samples in People Living with HIV/AIDS (PLWHA) in China: A Prospective Study
Author(s) -
Peize Zhang,
HouMing Liu,
Hui Wang,
Yanbo Wu,
Liqin Sun,
Man Rao,
Xinyun Jia,
Ying Song,
Guofang Deng,
LI Tian-pin,
Feidi Ye,
Yang Zhou,
YiChu Liao
Publication year - 2021
Publication title -
hiv/aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 22
ISSN - 1179-1373
DOI - 10.2147/hiv.s319117
Subject(s) - medicine , sputum , bronchoalveolar lavage , tuberculosis , mycobacterium tuberculosis , virology , immunology , pathology , lung
Sputum is commonly used for the diagnostic testing of pulmonary tuberculosis (PTB), but people living with HIV/AIDS (PLWHA) usually have little sputum. Moreover, the automated molecular test, Xpert MTB/RIF assay (Xpert), has a low sensitivity in PLWHA. We aimed to estimate the performance of Xpert Ultra on the detection of Mycobacterium tuberculosis (MTB) using bronchoalveolar lavage (BAL).