Open AccessEffect of Isoniazid Prophylaxis Therapy on the Prevention of Tuberculosis Incidence and Associated Factors Among HIV Infected Individuals in Northwest Ethiopia: Retrospective Cohort Study
Author(s) -
Mulat Addis Bishaw,
Shitaye Alemu Balcha,
Ayenew Molla Lakew
Publication year - 2021
Publication title -
hiv/aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 22
ISSN - 1179-1373
DOI - 10.2147/hiv.s301355
Subject(s) - medicine , tuberculosis , hazard ratio , isoniazid , incidence (geometry) , cohort , proportional hazards model , retrospective cohort study , confidence interval , pathology , physics , optics
Treating latent tuberculosis (TB) infection with Isoniazid (INH) among human immune virus (HIV) infected patients reduces active TB occurrence and death by 62% and 26%, respectively. Even though other studies show aforementioned evidence, TB incidence and its associated factors among HIV-infected individuals who were on INH and never on INH is not well studied in northwest Ethiopia. Therefore, this study tried to assess the effect of INH prophylaxis in TB prevention and associated factors among HIV-infected individuals.