Open AccessMucoadhesive Microspheres of Maraviroc and Tenofovir Designed for Pre-Exposure Prophylaxis of HIV-1: An in vitro Assessment of the Effect on Vaginal Lactic Acid Bacteria Microflora
Author(s) -
Sabdat Ozichu Ekama,
Margaret O. Ilomuanya,
Chukwuemeka P. Azubuike,
Tajudeen Akanji Bamidele,
Muinah Fowora,
Oluwagbemiga Aina,
Oliver Ezechi,
C. I. Igwilo
Publication year - 2021
Publication title -
hiv/aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 22
ISSN - 1179-1373
DOI - 10.2147/hiv.s291065
Subject(s) - maraviroc , mucoadhesion , lactobacillus fermentum , microbiology and biotechnology , microbicide , chemistry , enterococcus faecalis , bioavailability , lactic acid , bacteria , pharmacology , medicine , human immunodeficiency virus (hiv) , biology , virology , drug delivery , bioadhesive , staphylococcus aureus , organic chemistry , genetics , lactobacillus plantarum
To formulate and evaluate microspheres of the antiretroviral drugs maraviroc and tenofovir intended for a candidate vaginal microbicide and assess its effect on the vaginal lactic acid bacteria microflora.