Open AccessEfficacy and Safety of Proton Beam Therapy for Primary Optic Nerve Sheath Meningioma
Author(s) -
Rabih Hage,
Claire Alapetite,
H. Brisse,
Kévin Zuber,
Augustin Lecler,
Guillaume Lot,
C. Le Guérinel,
C. Vignal-Clermont,
Hervé Boissonnet
Publication year - 2021
Publication title -
eye and brain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.017
H-Index - 15
ISSN - 1179-2744
DOI - 10.2147/eb.s305822
Subject(s) - medicine , optic nerve , ophthalmology , fundus (uterus) , visual acuity , optic disc , optic disk , pallor , optic neuropathy , radiation therapy , surgery , meningioma , optic canal , glaucoma
Management of optic nerve sheath meningiomas (ONSM) remains challenging. Photon radiation therapy (PhRT) is the most common treatment for sight-threatening ONSM. Proton beam therapy (PBT) is less commonly used because it is more expensive and because there are questions about its efficacy specifically in relation to ONSM. PBT has the theoretical advantage of reducing radiation exposure to adjacent structures. We report the visual outcome of patients with primary ONSM managed at the Fondation Ophtalmologique Adolphe de Rothschild, Paris, France, and treated with PBT at the Centre de Protonthérapie, Institut Curie, Orsay, France.