Open AccessRelationship of Bone Turnover Markers with Serum Uric Acid-to-Creatinine Ratio in Men and Postmenopausal Women with Type 2 Diabetes
Author(s) -
Yingbin Xing,
Jing Liu,
Huanxin Liu,
Huijuan Ma
Publication year - 2022
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s384694
Subject(s) - medicine , creatinine , endocrinology , bone remodeling , n terminal telopeptide , confounding , uric acid , renal function , diabetes mellitus , type 2 diabetes mellitus , osteocalcin , alkaline phosphatase , biology , biochemistry , enzyme
Accumulating evidence has shown that serum uric acid (UA) is associated with some chronic diseases owing to its antioxidant capacity; however, previous research has discrepant results regarding the relationship between UA and bone health. UA normalized by renal function can reflect endogenous UA levels more precisely than SUA levels. This study assessed the relationship between serum UA-to-creatinine (SUA/Cr) ratio and bone turnover markers (BTMs) in men and postmenopausal women with type 2 diabetes mellitus (T2DM).