Open AccessUtility of Adipokines and IL-10 in Association with Anthropometry in Prediction of Insulin Resistance in Obese Children
Author(s) -
Asmaa A El Sehmawy,
Fatma Elzhraa Ahmed Diab,
Donia Ahmed Hassan,
Doaa Sayed Mohammed,
Mona Gamal El Din Al Anany,
Noha Abdel-Rahman Eldesoky,
Reham Y Elamir
Publication year - 2022
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s377072
Subject(s) - insulin resistance , medicine , adipokine , endocrinology , triglyceride , insulin , lipocalin , obesity , anthropometry , lipid profile , waist , cholesterol
This is a case-controlled study, with two hundred children enrolled. They were divided into an obese group of 100 children who had BMI ≥ 95th percentile according to CDC criteria and a group of 100 children with normal weight. All enrolled children were subjected to detailed medical history and clinical examination, in addition to measuring fasting blood sugar, fasting serum insulin, HOMA-IR calculation, lipid profile analysis, total serum cholesterol, low- and high-density lipoproteins (LDL and HDL), and serum triglyceride (TG). Two adipokines (lipocalin-2 and adipsin) serum levels plus IL-10 serum level were assessed.