Open AccessHTR1A Gene Polymorphism in Type 2 Diabetes Mellitus Comorbid with Major Depressive Disorder in a Chinese Population
Author(s) -
Dilixia Simayi,
Yihui Guan
Publication year - 2022
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s361843
Subject(s) - type 2 diabetes , depression (economics) , diabetes mellitus , medicine , single nucleotide polymorphism , genotyping , major depressive disorder , type 2 diabetes mellitus , polymorphism (computer science) , endocrinology , genotype , gene , genetics , biology , amygdala , economics , macroeconomics
Major depressive disorder is a frequent mental illness, which is common in patients with type 2 diabetes. Type 2 diabetes comorbid with depression has a worse prognosis. There are multiple risk factors for depression, and genetic studies have shown that gene polymorphism may play an important role in the pathogenesis of depression.