Open AccessAssociation of Serum Amylase Activity and the Copy Number Variation of AMY1/2A/2B with Metabolic Syndrome in Chinese Adults
Author(s) -
Fangjie Zhan,
Jin Chen,
Yan H,
Shuiliang Wang,
Meng Zhao,
Shenghang Zhang,
Xiaopeng Lan,
Masato Maekawa
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s339604
Subject(s) - amylase , medicine , metabolic syndrome , endocrinology , area under the curve , biomarker , anthropometry , uric acid , obesity , biology , enzyme , biochemistry
Low serum amylase activity and copy number (CN) variation (CNV) of the salivary amylase gene ( AMY1 ) are reportedly associated with obesity and abnormal glucose metabolism; however, this association remains controversial. We aimed to clarify the relationship between serum amylase activity and the CNV of AMY1/2A/2B with the occurrence of metabolic syndrome (MetS) in Chinese adults.