Open AccessInflammatory Biomarkers Levels in T2DM Emirati Patients with Diabetic Neuropathy
Author(s) -
Bashair M. Mussa,
Ankita Srivastava,
Abeer Al-Habshi,
Abdul Khader Mohammed,
Rabih Halwani,
Salah Abusnana
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s319863
Subject(s) - medicine , diabetic neuropathy , diabetes mellitus , intensive care medicine , endocrinology
Previous studies have suggested the involvement of chronic low-grade inflammation in the pathogenesis of diabetic neuropathy (DNP). However, none of these studies have examined the levels of monocyte chemoattractant protein-1 (MCP-1) in type 2 diabetes mellitus (T2DM) patients with confirmed diagnosis of neuropathy. Therefore, the present study aims to investigate the levels of MCP-1 along with IL-6, IL-8 and TGF-β in patients with T2DM and confirmed neuropathy and identify correlations, if any, between MCP-1 and other parameters.