Open AccessInterhemispheric Functional Connectivity Alterations in Diabetic Optic Neuropathy: A Resting-State Functional Magnetic Resonance Imaging Study
Author(s) -
Song Tan,
Guoqian Cai,
Qiuyu Li,
Yu Guo,
YiCong Pan,
Lijuan Zhang,
QianMin Ge,
HuiYe Shu,
Xianjun Zeng,
Yi Shao
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s303782
Subject(s) - cingulum (brain) , functional magnetic resonance imaging , resting state fmri , corpus callosum , medicine , magnetic resonance imaging , receiver operating characteristic , functional connectivity , neuroscience , psychology , audiology , radiology , white matter , fractional anisotropy
Previous research suggests that diabetic optic neuropathy (DON) can cause marked anatomical and functional variations in the brain, but to date altered functional synchronization between two functional hemispheres remains uncharacterized in DON patients. Voxel mirrored homotopic connectivity (VMHC) is a voxel-based method to evaluate the synchronism between two mirrored hemispheric by determining the functional connectivity between each voxel in one hemisphere and its counterpart. In this study, we aim to assess abnormal changes in interhemispheric functional connectivity in DON patients via the VMHC method.