Open AccessThe Involvement of Selenium in Type 2 Diabetes Development Related to Obesity and Low Grade Inflammation
Author(s) -
Rossukon Wongdokmai,
Prapimporn Chattranukulchai Shantavasinkul,
Suwannee Chanprasertyothin,
Pachara Panpunuan,
Dujrudee Matchariyakul,
Piyamitr Sritara,
Jintana Sirivarasai
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s303146
Subject(s) - prediabetes , medicine , glycated hemoglobin , overweight , type 2 diabetes , obesity , diabetes mellitus , body mass index , odds ratio , type 2 diabetes mellitus , micronutrient , selenium , endocrinology , pathology , materials science , metallurgy
Effects of the micronutrient selenium have been proposed in obesity and type 2 diabetes mellitus (T2DM) that involve impairments in glucose metabolic pathways and the insulin signaling cascade, mediated through oxidative stress and inflammation. However, the evidence collected to date through animal and epidemiologic studies has been inconclusive. Therefore, in the present study, we aimed to evaluate the relationships of selenium status and inflammation with T2DM and obesity.