Open AccessAstragaloside IV Inhibits Mitochondrial-Dependent Apoptosis of the Dorsal Root Ganglion in Diabetic Peripheral Neuropathy Rats Through Modulation of the SIRT1/p53 Signaling Pathway
Author(s) -
Ying Ben,
Juan Huang,
Zhihong Zhang,
Yun-Zhao Xiong,
Cuijuan Zhang,
Yi Chang,
Fan Yang,
Hui Li,
Tianya Zhang,
Xiangting Wang,
Qin Xu
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s301068
Subject(s) - dorsal root ganglion , apoptosis , peripheral neuropathy , dorsum , peripheral , mitochondrion , microbiology and biotechnology , chemistry , medicine , pharmacology , biology , endocrinology , diabetes mellitus , anatomy , biochemistry
To investigate the effect of astragaloside IV (AS-IV) on mitochondrial-dependent apoptosis in the dorsal root ganglion of diabetic peripheral neuropathy (DPN) rats through the SIRT1/p53 pathway.