Open AccessDiabetes Mellitus Promotes Atrial Structural Remodeling and PARP-1/Ikkα/NF-κB Pathway Activation in Mice
Author(s) -
Tianyu Meng,
Jie Wang,
Manyun Tang,
Shangyu Liu,
Ligang Ding,
Yan Yang
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s300616
Subject(s) - inflammation , medicine , diabetes mellitus , endocrinology , atrial fibrillation , fibrosis , diabetic cardiomyopathy , heart failure , cardiomyopathy
Diabetes mellitus (DM) has been demonstrated to be linked to atrial fibrillation (AF). However, the underlying mechanisms of the DM-associated increase in AF susceptibility and the potential effects of DM on atrial remodeling remain unclear.