Open AccessGlutathione S-Transferase (GSTT1 rs17856199) and Nitric Oxide Synthase (NOS2 rs2297518) Genotype Combination as Potential Oxidative Stress-Related Molecular Markers for Type 2 Diabetes Mellitus
Author(s) -
Amani M T Gusti,
Safaa Qusti,
Suhad Bahijri,
Eman A. Toraih,
Samia A Bokhari,
Sami M Attallah,
Abdulwahab Alzahrani,
Wafaa M A Alshehri,
Hawazin Alotaibi,
Manal S. Fawzy
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s300525
Subject(s) - genotype , oxidative stress , glutathione peroxidase , type 2 diabetes mellitus , genotyping , medicine , biology , superoxide dismutase , diabetes mellitus , endocrinology , genetics , gene
Deregulation of the antioxidant enzymes was implicated in pathogenesis and complications of type 2 diabetes mellitus (T2DM). The data relate the genetic variants of these enzymes to T2DM are inconsistent among various populations.