Open AccessElectromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice
Author(s) -
Mingming Zhai,
Xiaoxing Yan,
Jiangzheng Liu,
Zi Long,
Shuai Zhao,
Wendan Li,
Ying Li,
Chen Hai
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s294020
Subject(s) - nonalcoholic fatty liver disease , steatosis , insulin resistance , medicine , endocrinology , fatty liver , oxidative stress , glutathione , triglyceride , homeostasis , insulin , chemistry , biochemistry , disease , cholesterol , enzyme
The prevalence of nonalcoholic fatty liver disease (NAFLD), which has recently become known as metabolic-associated fatty liver disease (MAFLD), has risen. However, pharmacotherapies for this disease have not been approved. Electromagnetic fields (EMFs) have excellent bioeffects on multiple diseases. However, the effects of EMFs on NAFLD are unknown. This study investigated the bioeffects of EMF exposure on insulin resistance, liver redox homeostasis and hepatic steatosis in db/db mice.