Open AccessCharacteristics of Gut Microbiota in Cerulein-Induced Chronic Pancreatitis
Author(s) -
ChinChen Wu,
Mengmeng Li,
Wenji Chen
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s291822
Subject(s) - firmicutes , gut flora , bacteroidetes , biology , akkermansia , actinobacteria , pancreatitis , microbiome , verrucomicrobia , medicine , physiology , bacteroides , immunology , bacteria , bioinformatics , genetics , 16s ribosomal rna
Although clinical trials and animal models have evaluated the alterations of the microbiome in chronic pancreatitis (CP), the gut microbiota composition and diversity in cerulein-induced CP is unknown. This study aimed to evaluate the changes of gut microbiota in a CP mice model, and to determine whether these gut microbiota changes were consistent with those in patients with CP.