Open AccessSerum Heparanase: A New Clinical Biomarker Involved in Senile Metabolic Inflammatory Syndrome
Author(s) -
Qingsong Wang,
Xiaoyan Zhou,
Guanghai Mei,
Jiantao Wang,
Zhongyu Yu,
Yue Hu,
Xinyu Guo,
Hanyu Zhang,
Xiaodie Xu,
Chengfeng He,
Jun Guo,
Yong Tao,
Houguang Zhou
Publication year - 2021
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s291612
Subject(s) - medicine , inflammation , heparanase , biomarker , gastroenterology , c reactive protein , metabolic syndrome , population , blood lipids , immunology , endocrinology , obesity , cancer , cholesterol , biology , biochemistry , environmental health , metastasis
Metabolic inflammation syndrome (MIS) can lead to a series of complications, but its exact inflammatory mechanism is still unclear. The aim of this study was to explore the correlation between heparanase (HPA) and MIS, and the close relationship between HPA and other chronic low-grade inflammation index, such as C-reactive protein (CRP) and interleukin-6 (IL-6).