Open Access<p>Identification of Genetic Variants for Female Obesity and Evaluation of the Causal Role of Genetically Defined Obesity in Polycystic Ovarian Syndrome</p>
Author(s) -
Yeongseon Ahn,
Hyejin Lee,
Yoon Shin Cho
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s281529
Subject(s) - mendelian randomization , obesity , body mass index , genome wide association study , waist , genetic association , polycystic ovary , population , medicine , biology , genetics , endocrinology , single nucleotide polymorphism , genotype , genetic variants , insulin resistance , gene , environmental health
Observational studies have demonstrated an increased risk of polycystic ovarian syndrome (PCOS) in obese women. This study aimed to identify genetic variants influencing obesity in females and to evaluate the causal association between genetically defined obesity and PCOS in Korean women.