Open Access<p>Effect and Mechanism of <em>Ganoderma lucidum</em> Spores on Alleviation of Diabetic Cardiomyopathy in a Pilot in vivo Study</p>
Author(s) -
Fahmi Shaher,
Shuqiu Wang,
Hongbin Qiu,
Yu Hu,
Yu Zhang,
Weiqun Wang,
Hisham Al-Ward,
Mahfoudh Abdulghani,
Salem Baldi,
Shaobo Zhou
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s281527
Subject(s) - diabetic cardiomyopathy , medicine , western blot , streptozotocin , pioglitazone , glycogen , endocrinology , diabetes mellitus , fibrosis , cardiomyopathy , pharmacology , type 2 diabetes , chemistry , biochemistry , heart failure , gene
Ganoderma lucidum spores (GLS) exhibit disease prevention properties, but no study has been carried out on the anti-diabetic cardiomyopathy property of GLS. The aim of this study was to evaluate the hyperglycemia-mediated cardiomyopathy protection and mechanisms of GLS in streptozotocin (STZ)induced diabetic rats.