Open Access<p><em>CHDH-PNPLA3</em> Gene–Gene Interactions Predict Insulin Resistance in Children with Obesity</p>
Author(s) -
Adela Chirita-Emandi,
Costela Lăcrimioara Șerban,
Corina Paul,
Nicoleta Andreescu,
Iulian Velea,
Alexandra Mihăilescu,
Vlad Serafim,
Diana-Andreea Tiugan,
Paul Tuțac,
Cristian G. Zimbru,
Maria Puiu,
Mihai D. Niculescu
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s277268
Subject(s) - insulin resistance , endocrinology , medicine , single nucleotide polymorphism , obesity , insulin , choline , fatty liver , homeostatic model assessment , biology , metabolic syndrome , body mass index , genotype , genetics , gene , disease
Insulin resistance plays a major role in metabolic syndrome and is recognized as the most common risk factor for non-alcoholic fatty liver disease (NAFLD). Identifying predictors for insulin resistance could optimize screening and prevention.