Open Access<p>Isomangiferin Attenuates Renal Injury in Diabetic Mice via Inhibiting Inflammation</p>
Author(s) -
Shuwen Yue,
Ning Xue,
Honglei Li,
Zhen Chen,
Baosheng Huang,
Xing Wang
Publication year - 2020
Publication title -
diabetes, metabolic syndrome and obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.853
H-Index - 43
ISSN - 1178-7007
DOI - 10.2147/dmso.s276229
Subject(s) - hmgb1 , inflammation , medicine , endocrinology , kidney , creatinine , diabetes mellitus , proinflammatory cytokine , uric acid , western blot , pharmacology , chemistry , biochemistry , gene
Renal injury induced by diabetes is reported to be associated with inflammation. Isomangiferin (ISO), a xanthone C-glucoside from the Cyclopia subfamily, exhibits many pharmacological properties. This study aimed to evaluate the protection of ISO against renal damage in diabetic mice.